Gene information
Official symbol C5AR2
Official full name complement component 5a receptor 2
Gene type protein-coding gene
Chromosome19q13.32
Alias symbolC5L2
Previous symbolGPR77
Gene familyComplement component GPCRs
Resources
Entrez Gene 27202
HGNC HGNC:4527
Ensembl ENSG00000134830
Vega OTTHUMG00000183505
UCSC uc010ela.2
GO terms: 28 records
GO Description Category LogP Number of genes Detail
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0002683 negative regulation of immune system process GO Biological Processes -26.6415063 77 More
GO:0002686 negative regulation of leukocyte migration GO Biological Processes -7.70467721 14 More
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway GO Biological Processes -11.6592522 24 More
GO:0007204 positive regulation of cytosolic calcium ion concentration GO Biological Processes -15.6883547 39 More
GO:0030336 negative regulation of cell migration GO Biological Processes -30.9008082 37 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0032675 regulation of interleukin-6 production GO Biological Processes -28.2553997 51 More
GO:0032677 regulation of interleukin-8 production GO Biological Processes -20.0046302 33 More
GO:0032680 regulation of tumor necrosis factor production GO Biological Processes -32.0729913 56 More
GO:0032715 negative regulation of interleukin-6 production GO Biological Processes -14.4703936 13 More
GO:0032720 negative regulation of tumor necrosis factor production GO Biological Processes -18.6356508 28 More
GO:0040013 negative regulation of locomotion GO Biological Processes -30.7871461 81 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0045177 apical part of cell GO Cellular Components -8.17813885 46 More
GO:0050678 regulation of epithelial cell proliferation GO Biological Processes -51.9930445 102 More
GO:0050679 positive regulation of epithelial cell proliferation GO Biological Processes -31.4834672 59 More
GO:0050922 negative regulation of chemotaxis GO Biological Processes -8.57011989 17 More
GO:0051271 negative regulation of cellular component movement GO Biological Processes -29.9238399 37 More
GO:0070372 regulation of ERK1 and ERK2 cascade GO Biological Processes -38.4320790 79 More
GO:0070374 positive regulation of ERK1 and ERK2 cascade GO Biological Processes -34.9831828 64 More
GO:0090022 regulation of neutrophil chemotaxis GO Biological Processes -5.21154381 9 More
GO:0140375 immune receptor activity GO Molecular Functions -8.53513203 25 More
GO:1902622 regulation of neutrophil migration GO Biological Processes -4.86040077 10 More
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -32.3948799 57 More
GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -18.2876323 28 More
GO:2000146 negative regulation of cell motility GO Biological Processes -30.256132 37 More
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
C5AR2 transcriptomics tocilizumab[treatment (pharmacotherapy)] acute non-ST elevation myocardial infarction Orrem HL et al. Front Immunol. 2018
C5AR2 transcriptomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Orrem HL et al. Front Immunol. 2018
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